Luteinization of porcine preovulatory follicles leads to systematic changes in follicular gene expression

Preovulatory changes in morphology of rabbit ovarian follicles.

To examine timed changes in the morphology of theca interna and granulosa cells of rabbit preovulatory follicles, mature female rabbits were injected with100 IU per kg of human chorionic gonadotropin (hCG) and follicles larger than1mn in diameter were excised for light and electron microscopic studies before and3, 6, 9and 12hr after hCG injection. Spindle-shaped theca interna cells had been tra...

Human ovarian follicular development: from activation of resting follicles to preovulatory maturation.

By integrating morphometrical and endocrinological data, as well as biological effects of various molecules synthesized by the human follicle, we propose a dynamic view of the follicle growth within the human ovary. Folliculogenesis starts with entry of resting follicles into the growth phase, a process where the kit system plays a key role. Several months are required for a new growing follicl...

Human chorionic gonadotropin-dependent regulation of 17beta-hydroxysteroid dehydrogenase type 4 in preovulatory follicles and its potential role in follicular luteinization.

17Beta-hydroxysteroid dehydrogenase type 4 (17betaHSD4) has a unique multidomain structure, with one domain involved in 17beta-estradiol inactivation. The objective of the study was to investigate the regulation of 17betaHSD4 during human chorionic gonadotropin (hCG)-induced ovulation/luteinization. The equine 17betaHSD4 cDNA was cloned and was shown to encode a 735-amino acid protein that is h...

Progestagen dynamics in preovulatory follicles of rats.

Programmed cell death in preovulatory ovine follicles.

Apoptosis is a mode of physiological cell death that occurs during tissue regression and remodeling; it is characterized by macromolecular protein synthesis, oligonucleosomal fragmentation, nuclear condensation, cytoplasmic shrinkage, and dissociation of cell-to-cell junctional complexes. Direct in situ fluorescence detection of digoxigenin end-labeled genomic DNA was used as a marker of nuclea...